Opportunity Information: Apply for 72061121RFA00001
The Service Delivery for HIV Prevention opportunity (Funding Opportunity Number 72061121RFA00001) is a USAID Zambia (USAID-Lusaka) discretionary funding opportunity designed to reduce new HIV infections and improve overall health outcomes in Zambia. The central focus is prevention among priority populations and key populations who face the highest risk of acquiring HIV, with an emphasis on practical, proven approaches that can be expanded to reach more people and deliver measurable impact at scale. In plain terms, the grant is meant to push effective prevention and case-finding strategies beyond small or pilot efforts and into broader, routine service delivery so fewer people acquire HIV and more people who already have HIV are identified earlier and connected to care.
A major part of the activity is sustaining HIV-negative status among people who are currently HIV negative. That typically means strengthening and expanding evidence-based HIV prevention interventions that are already known to work, and ensuring they are delivered consistently to the groups and communities where risk is highest. While the notice does not list every intervention, the framing is clearly about scaling proven prevention service delivery rather than experimenting with untested ideas. The goal is to make prevention services easier to access, better targeted to those at highest risk, and strong enough in coverage and quality that they meaningfully reduce transmission.
Another core component is finding people living with HIV who have not yet been diagnosed and linking them to treatment. The opportunity highlights the gap that often exists between people who are infected and people who know their status, and it positions this activity as a way to close that gap by improving identification and linkage to antiretroviral treatment through coordinated service delivery. The underlying public health logic is straightforward: when people with HIV are diagnosed early and started on effective treatment, their health outcomes improve and onward transmission is reduced, supporting both individual well-being and epidemic control goals.
The opportunity also places special emphasis on scaling up recency testing in close collaboration with clinical implementing partners and the Government of Zambia. Recency testing is described as a tool that can quickly identify individuals who have been newly infected with HIV, which can help programs respond faster and more strategically to emerging transmission patterns. By identifying recent infections, implementers and government counterparts can better understand where transmission is happening now (not just historically), allowing prevention efforts to be more targeted and timely. The notice presents recency testing as an important, proven approach for strengthening HIV prevention and helping to stem the spread of the virus when paired with appropriate follow-up actions and coordination across partners.
From a funding and award structure perspective, USAID planned to issue this as a Cooperative Agreement, which usually means the agency expects substantial involvement during implementation, such as collaboration on workplanning, technical direction, monitoring, and coordination with other USAID and government-supported efforts. The award ceiling listed is up to USD 75,000,000, and USAID anticipated making three awards, suggesting the activity could be implemented through multiple partners or geographic and programmatic components to increase coverage and reach. The opportunity falls under the Health funding activity category and is associated with CFDA number 98.001, reflecting USAID foreign assistance programming.
In terms of eligibility, the listing indicates "Others (see text field entitled Additional Information on Eligibility for clarification)," which implies the detailed eligibility criteria were provided in the full solicitation rather than in the brief summary data. The opportunity was created on February 2, 2021, with an original closing date of March 5, 2021, indicating a defined application window for prospective applicants at that time. Overall, the opportunity is best understood as a large-scale, partner-coordinated effort to expand effective HIV prevention service delivery, improve identification of undiagnosed HIV infections, strengthen linkage to treatment, and use recency testing more widely to sharpen and accelerate prevention responses in Zambia.Apply for 72061121RFA00001
- The Agency for International Development, Zambia USAID-Lusaka in the health sector is offering a public funding opportunity titled "Service Delivery for HIV Prevention" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 98.001.
- This funding opportunity was created on Feb 02, 2021.
- Applicants must submit their applications by Mar 05, 2021. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $75,000,000.00 in funding.
- The number of recipients for this funding is limited to 3 candidate(s).
- Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
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