Opportunity Information: Apply for PAR 20 140
The grant opportunity titled "Catalytic Tool and Technology Development in Kidney, Urologic, and Hematologic Diseases (R21 Clinical Trial Not Allowed)" (Funding Opportunity Number PAR 20 140) is a National Institutes of Health (NIH) discretionary grant program under the U.S. Department of Health and Human Services. Its core goal is to accelerate the creation of innovative tools and enabling technologies that can push research forward in three broad biomedical areas: kidney diseases, urologic diseases, and hematologic (blood-related) diseases. The emphasis is on catalytic, early-stage development work that helps the field overcome technical bottlenecks, improves what researchers can measure or build, or opens up entirely new experimental or diagnostic capabilities. As an R21 mechanism, it is generally aimed at exploratory and developmental projects rather than large, long-term, hypothesis-driven programs.
A key feature of this opportunity is that it is explicitly "Clinical Trial Not Allowed," meaning proposed work should not involve clinical trial activities as defined by NIH. In practice, this steers applicants toward preclinical development, validation, and demonstration projects, as well as tool-building efforts that may use clinical samples or datasets in certain compliant ways, but without conducting an interventional or prospective clinical trial. The announcement is meant to support technology-oriented research that can serve as a platform for later translational steps, including future clinical studies funded through other mechanisms once the tool or method is sufficiently mature.
The funding instrument is a grant within the NIH R21 framework, and the opportunity lists an award ceiling of $200,000. The announcement indicates an expectation of about 10 awards, signaling a competitive program that intends to fund a small set of projects with clear technical novelty and high potential to enable downstream discoveries or applications. The activity category is listed under health (and broadly categorized in the source data alongside "Food and Nutrition, Health"), and the associated CFDA number is 93.847, which corresponds to NIH support areas connected to diabetes, endocrine, metabolic, and related kidney and urologic research portfolios (depending on NIH institute alignment and interpretation of that CFDA listing).
Eligibility is broad and includes many organization types, reflecting NIH norms for tool and technology development. Eligible applicants include state, county, and city/township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; other tribal organizations; public housing authorities/Indian housing authorities; nonprofits with and without 501(c)(3) status (excluding institutions of higher education when specified); for-profit organizations other than small businesses; small businesses; and additional categories described in the announcement's eligibility text. This breadth is consistent with the program's focus on enabling technologies, where innovation may come from academic labs, nonprofit research institutes, startups, or established companies, sometimes in collaboration.
From a practical standpoint, the kinds of projects this opportunity is designed to support typically include development of new research tools, novel measurement technologies, improved assays, computational methods, data resources, model systems, imaging or sensing approaches, devices for experimental use, or other technical platforms that address unmet needs in kidney, urologic, or hematologic disease research. The term "catalytic" signals that the NIH is looking for work that can unlock progress for many researchers, not just answer a narrow scientific question. Reviewers generally look for a strong rationale for why the tool is needed, what makes it innovative relative to existing options, and whether the team has a credible plan to build and demonstrate it within the limited scope and budget typical of an R21.
The opportunity was created on March 16, 2020, and the original closing date listed is May 7, 2023. Applicants considering similar opportunities should note that NIH funding announcements can be reissued, updated, or replaced over time, so it is important to verify the current status, active receipt dates, and any updated instructions in the live NIH posting and associated application guide.Apply for PAR 20 140
- The Department of Health and Human Services, National Institutes of Health in the food and nutrition, health sector is offering a public funding opportunity titled "Catalytic Tool and Technology Development in Kidney, Urologic, and Hematologic Diseases (R21 Clinical Trial Not Allowed)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.847.
- This funding opportunity was created on Mar 16, 2020.
- Applicants must submit their applications by May 07, 2023. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $200,000.00 in funding.
- The number of recipients for this funding is limited to 10 candidate(s).
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification).
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Applicants also applied for:
Applicants who have applied for this opportunity (PAR 20 140) also looked into and applied for these:
| Funding Opportunity |
|---|
| George M. O'Brien Urology Cooperative Research Centers Program (U54 Clinical Trial Optional) Apply for RFA DK 20 008 Funding Number: RFA DK 20 008 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $1,000,000 |
| NIDDK Catalyst Award (DP1 Clinical Trial Not Allowed) Apply for RFA DK 20 024 Funding Number: RFA DK 20 024 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $500,000 |
| NIDDK Research Education Program Utilizing Stimulating Peripheral Activity to Relieve Conditions (SPARC) - Generated Resources (R25 Clinical Trial Not Allowed) Apply for RFA DK 20 020 Funding Number: RFA DK 20 020 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $120,000 |
| Reconfiguration of GenitoUrinary Development Molecular Anatomy Project (GUDMAP) /(Re)Building A Kidney (RBK) Data Hub (U24 Clinical Trial Not Allowed) Apply for RFA DK 20 014 Funding Number: RFA DK 20 014 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $750,000 |
| Pilot and Feasibility Studies to Facilitate the Use of Diabetes Self-Management Education and Support to Improve Diabetes Care (R34 Clinical Trial Required) Apply for RFA DK 20 032 Funding Number: RFA DK 20 032 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $225,000 |
| Understanding and Reducing Cardiovascular Disease in Type 1 Diabetes Mellitus (R01 Clinical Trial Optional) Apply for RFA HL 21 014 Funding Number: RFA HL 21 014 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $500,000 |
| Limited Competition: Revision to the Longitudinal Monitoring of Pancreas Architecture in the Type 1 Diabetes in Acute Pancreatitis Consortium - Data Coordinating Center (T1DAPC-DCC) (U01 Clinical Trial Optional) Apply for RFA DK 21 501 Funding Number: RFA DK 21 501 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $1,500,000 |
| Standardization of C-Peptide and HbA1C Measurements Program (U01 Clinical Trial Not Allowed) Apply for RFA DK 21 007 Funding Number: RFA DK 21 007 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $350,000 |
| Advance conformance with the Voluntary National Retail Food Regulatory Program Standards (VNRFRPS) Apply for FOR FD 20 021 Funding Number: FOR FD 20 021 Agency: Department of Health and Human Services, Food and Drug Administration Category: Food and Nutrition, Health Funding Amount: Case Dependent |
| Manufactured Food Regulatory Program Alliance Apply for FOR FD 20 020 Funding Number: FOR FD 20 020 Agency: Department of Health and Human Services, Food and Drug Administration Category: Food and Nutrition, Health Funding Amount: Case Dependent |
| FDA Support for Conferences and Scientific Meetings (R13 Clinical Trial Not Allowed) Apply for PAR 23 072 Funding Number: PAR 23 072 Agency: Department of Health and Human Services, Food and Drug Administration Category: Food and Nutrition, Health Funding Amount: Case Dependent |
| Enhancing Local Achievements in Nutrition Excellence (ELAINE) Apply for 7200AA23RFA00008 Funding Number: 7200AA23RFA00008 Agency: Agency for International Development Category: Food and Nutrition, Health Funding Amount: $99,500,000 |
| Produce Prescription Pilot Program Apply for HHS 2023 IHS PPPP 0001 Funding Number: HHS 2023 IHS PPPP 0001 Agency: Department of Health and Human Services, Indian Health Service Category: Food and Nutrition, Health Funding Amount: $500,000 |
| Egg Safety Regulatory Program Standards Development (U18) Apply for RFA FD 16 040 Funding Number: RFA FD 16 040 Agency: Food and Drug Administration Category: Food and Nutrition, Health Funding Amount: $150,000 |
| Limited Competition: Understanding How Epigenetics and Infections Impact Autoimmunity and Diabetes in The Environmental Determinants of Diabetes In The Young Study (TEDDY) (UC4) Apply for RFA DK 15 506 Funding Number: RFA DK 15 506 Agency: National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $22,000,000 |
| Diabetes Research Centers (P30) Apply for RFA DK 15 026 Funding Number: RFA DK 15 026 Agency: National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $1,000,000 |
| Assay Development and Screening to Discover Therapeutic or Imaging Agents for Diseases of Interest to the NIDDK (R01) Apply for PA 16 374 Funding Number: PA 16 374 Agency: National Institutes of Health Category: Food and Nutrition, Health Funding Amount: Case Dependent |
| Limited Competition: Continuation of the Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness (GRADE) Study (U01) Apply for RFA DK 16 511 Funding Number: RFA DK 16 511 Agency: National Institutes of Health Category: Food and Nutrition, Health Funding Amount: Case Dependent |
| Limited Competition for the Continuation of Epidemiology of Diabetes Interventions and Complications (EDIC) Study Clinical Research Center (Collaborative U01) Apply for RFA DK 16 508 Funding Number: RFA DK 16 508 Agency: National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $3,500,000 |
| Limited Competition for the Continuation of Epidemiology of Diabetes Interventions and Complications (EDIC) Study Biostatistics Research Center (Collaborative U01) Apply for RFA DK 16 509 Funding Number: RFA DK 16 509 Agency: National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $2,500,000 |
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