Opportunity Information: Apply for PA 18 199
The funding opportunity titled "Screening and Brief Alcohol Interventions in Underage and Young Adult Populations (R21 Clinical Trial Optional)" (Funding Opportunity Number PA 18 199) is a National Institutes of Health (NIH) discretionary grant solicitation focused on improving public health by preventing or reducing alcohol use and alcohol-related harms in underage individuals and young adults. The central aim of the announcement is to support research that tests, refines, or develops screening approaches and brief interventions that can be used to identify risky drinking and quickly deliver practical, evidence-informed support to reduce harm. The emphasis on "screening and brief interventions" signals interest in strategies that are relatively low-burden and scalable, such as short assessments for alcohol risk and concise counseling, feedback, or motivational approaches that can be delivered in common real-world settings (for example, schools, clinics, colleges, community programs, or other youth-serving environments). The "R21" mechanism indicates an exploratory/developmental type of award, typically used to generate early evidence, pilot novel approaches, or establish feasibility for larger future studies, and the listing notes that a clinical trial is optional, meaning applicants may propose either clinical-trial or non-clinical-trial research designs depending on the project.
The opportunity falls under the Health funding activity category and is associated with CFDA number 93.273. While the announcement is NIH-led, the scope is specifically targeted to the underage and young adult period, when alcohol initiation, escalation, and related consequences (injury, academic problems, risky sexual behavior, violence exposure, legal issues, and progression toward alcohol use disorder) can be especially pronounced. Projects supported under this FOA would generally be expected to contribute actionable knowledge about what works, for whom it works, and in what contexts brief screening and intervention methods can most effectively reduce drinking or prevent alcohol-related negative outcomes.
Eligibility is broad and includes many types of organizations that can credibly conduct health research or implement and evaluate interventions. Eligible applicants listed include state, county, and local governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; tribal organizations that are not federally recognized; public housing authorities and Indian housing authorities; nonprofits with or without 501(c)(3) status (excluding institutions of higher education where relevant); for-profit organizations other than small businesses; and small businesses. The FOA also explicitly highlights additional eligible applicant categories such as Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISIs); Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Tribally Controlled Colleges and Universities (TCCUs); faith-based or community-based organizations; eligible agencies of the federal government; regional organizations; U.S. territories or possessions; tribal governments other than federally recognized; and even non-U.S. (foreign) organizations. Taken together, this signals NIH interest in reaching diverse communities and supporting work in settings where underage and young adult drinking risks may differ due to geography, culture, access to services, or structural barriers.
From an award structure standpoint, the posted award ceiling is $200,000, aligning with the smaller, early-stage nature of the R21 mechanism. The original closing date shown in the source data is 2018-09-07, with a creation date of 2017-11-06, indicating the record reflects that funding cycle and timing. Even so, the content provides a clear picture of what NIH was seeking through this FOA: research that can strengthen the evidence base for practical screening tools and brief intervention strategies aimed at reducing alcohol use and related harms among adolescents and young adults, with flexibility around whether a clinical trial component is included.Apply for PA 18 199
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Screening and Brief Alcohol Interventions in Underage and Young Adult Populations (R21 Clinical Trial Optional)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.273.
- This funding opportunity was created on 2017-11-06.
- Applicants must submit their applications by 2018-09-07. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $200,000.00 in funding.
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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Frequently Asked Questions (FAQs)
What is the title of this funding opportunity?
The opportunity is titled "Screening and Brief Alcohol Interventions in Underage and Young Adult Populations (R21 Clinical Trial Optional)."
What is the Funding Opportunity Number (FON)?
The Funding Opportunity Number is PA 18 199.
Which agency is offering this grant?
This is a National Institutes of Health (NIH) discretionary grant solicitation.
What is the main purpose of this funding opportunity?
The purpose is to support research that improves public health by preventing or reducing alcohol use and alcohol-related harms among underage individuals and young adults, with a focus on screening approaches and brief interventions.
What kinds of projects does this FOA aim to support?
The FOA aims to support research that tests, refines, or develops alcohol risk screening approaches and brief interventions that can identify risky drinking and deliver practical, evidence-informed support to reduce harm.
What does "screening" mean in the context of this FOA?
Screening refers to relatively short assessments or approaches used to identify alcohol risk or risky drinking among underage individuals and young adults.
What does "brief alcohol interventions" mean in the context of this FOA?
Brief interventions are concise, low-burden strategies (such as short counseling, feedback, or motivational approaches) intended to quickly provide support that can reduce alcohol use or alcohol-related harms.
Why does the FOA emphasize "low-burden" and "scalable" strategies?
The FOA highlights approaches that can be delivered in common, real-world settings and may be easier to implement broadly, such as short assessments and concise intervention methods.
What settings are examples of where these approaches might be delivered?
Examples listed include schools, clinics, colleges, community programs, and other youth-serving environments.
Who is the target population for the research?
The target population is underage individuals and young adults, particularly during the period when alcohol initiation, escalation, and related consequences can be pronounced.
What types of harms or consequences are mentioned as relevant to this population?
The FOA notes consequences such as injury, academic problems, risky sexual behavior, violence exposure, legal issues, and progression toward alcohol use disorder.
What is the grant mechanism used for this opportunity?
This opportunity uses the NIH R21 mechanism, which is an exploratory/developmental award type.
What does the R21 mechanism generally indicate about the project stage?
R21 awards are typically used to generate early evidence, pilot novel approaches, or establish feasibility for larger future studies.
Is a clinical trial required?
No. The FOA states "Clinical Trial Optional," meaning applicants may propose either clinical-trial or non-clinical-trial research designs depending on the project.
What funding activity category is associated with this opportunity?
The opportunity falls under the Health funding activity category.
What is the CFDA number associated with this FOA?
The CFDA number associated with this opportunity is 93.273.
What is the award ceiling listed for this opportunity?
The posted award ceiling is $200,000.
How broad is eligibility for applicants?
Eligibility is broad and includes many organization types that can conduct health research or implement and evaluate interventions, including government entities, educational institutions, nonprofits, and for-profit entities (with specific notes on categories).
Which government entities are eligible to apply?
Eligible government applicants include state, county, and local governments; special district governments; and independent school districts.
Are public colleges and universities eligible?
Yes. Public and state-controlled institutions of higher education are eligible.
Are private colleges and universities eligible?
Yes. Private institutions of higher education are eligible.
Are nonprofit organizations eligible?
Yes. Nonprofits with or without 501(c)(3) status are eligible (excluding institutions of higher education where relevant, as described in the eligibility listing).
Are for-profit organizations eligible?
Yes. For-profit organizations other than small businesses are eligible, and small businesses are also listed as eligible.
Are tribal governments and tribal organizations eligible?
Yes. Federally recognized Native American tribal governments are eligible, and tribal organizations that are not federally recognized are also included. Tribal governments other than federally recognized are explicitly highlighted as eligible as well.
Are U.S. territories or possessions eligible?
Yes. U.S. territories or possessions are included among the highlighted eligible applicant categories.
Are regional organizations eligible?
Yes. Regional organizations are listed among the highlighted eligible applicant categories.
Are faith-based or community-based organizations eligible?
Yes. Faith-based or community-based organizations are explicitly highlighted as eligible applicants.
Are specific types of minority-serving institutions eligible?
Yes. The FOA highlights eligibility for Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISIs); Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); and Tribally Controlled Colleges and Universities (TCCUs).
Can federal agencies apply?
Yes. Eligible agencies of the federal government are included in the eligibility listing.
Are housing authorities eligible?
Yes. Public housing authorities and Indian housing authorities are listed as eligible applicants.
Are non-U.S. (foreign) organizations eligible to apply?
Yes. Non-U.S. (foreign) organizations are explicitly included as eligible.
What kinds of outputs or contributions are projects generally expected to make?
Projects are generally expected to contribute actionable knowledge about what works, for whom it works, and in what contexts brief screening and intervention methods can most effectively reduce drinking or prevent alcohol-related negative outcomes.
Why does the FOA focus on underage and young adult populations?
The FOA notes that the underage and young adult period can be a time when alcohol initiation, escalation, and related consequences are especially pronounced.
What is the closing date shown in the source information?
The original closing date shown is 2018-09-07.
What is the creation date shown for this record?
The creation date shown is 2017-11-06.
What does the timing information suggest about this listing?
The dates indicate the record reflects that funding cycle and timing, while still conveying what NIH was seeking through the FOA.
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