Opportunity Information: Apply for W81XWH 19 PRMRP TTDA

The CDMRP Peer Reviewed Medical Research Program (PRMRP) Technology/Therapeutic Development Award (TTDA) is a Department of Defense funding opportunity focused on moving strong preclinical research toward real-world medical products that can be used in clinical settings. Rather than supporting basic discovery science, this mechanism is designed for projects that are already showing promise in preclinical work and are ready for the next step: translation into a practical product with a clear path toward clinical application. The aim is to help bridge the common gap between early research results and the kind of development work needed to produce something that could ultimately be used to prevent, detect, diagnose, treat, or improve quality of life for patients.

The program is explicitly product-driven, meaning the proposed work should center on developing a tangible deliverable such as a therapeutic, technology platform, diagnostic tool, or other clinically relevant medical solution. Projects must align with at least one of the Congressionally directed FY19 PRMRP Topic Areas, which define the disease or condition priorities set for that fiscal year. A key expectation is relevance to military health: the product under development should be responsive to the healthcare needs of military Service members, Veterans, and/or other eligible beneficiaries. In practice, that usually implies a clear military or Veteran health rationale, such as addressing conditions prevalent in these populations, improving readiness, supporting recovery, or reducing long-term health burdens connected to service.

Administratively, this opportunity was issued by the Department of Defense, Department of the Army, through the U.S. Army Medical Research Acquisition Activity (USAMRAA), under funding opportunity number W81XWH 19 PRMRP TTDA. It was offered as a discretionary grant competition and could be funded through either a cooperative agreement or a grant, indicating that some awards may involve more direct federal involvement in project execution depending on the specific agreement structure. The activity falls under Science and Technology and other Research and Development and is associated with CFDA number 12.420, which is commonly used for DoD medical research assistance programs.

Eligibility was listed as unrestricted, meaning the opportunity was open to essentially any type of applicant organization or entity, with the caveat that applicants still needed to follow any eligibility clarifications described in the full announcement text. The opportunity opened on January 15, 2019, and had an original closing date of July 11, 2019. The program anticipated making around 16 awards. The listing shows an award ceiling of 0, which typically signals that the maximum dollar amount was not specified in that summary field and would instead be defined in the full solicitation or determined by program policy, project scope, and available appropriations.

Overall, the TTDA is best understood as a translational development mechanism: it supports the kind of applied R&D required to turn compelling preclinical evidence into a defined medical product intended for clinical use, with an emphasis on meeting the health needs of military and Veteran communities and staying aligned to the PRMRP topic priorities set by Congress for FY19.

  • The Department of Defense, Dept. of the Army -- USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "CDMRP Peer Reviewed Medical Research Program Technology/Therapeutic Development Award" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420.
  • This funding opportunity was created on Jan 15, 2019.
  • Applicants must submit their applications by Jul 11, 2019. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The number of recipients for this funding is limited to 16 candidate(s).
  • Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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